American Airlines is offering 50 AAdvantage miles per $1 donated to Stand Up To Cancer when you donate at least $25 with an eligible American Airlines Mastercard through September 30, 2026 (or until qualifying donations reach $5 million). You can earn the bonus on up to $10,000 in donations, but there are some caveats. The miles do not count toward Loyalty Points or elite status. If you make charitable donations annually or were already planning to donate, earning 50x AAdvantage miles is a nice little cherry on top. We wouldn't make a donation just to earn the miles. A $1,000 donation would earn about 51,000 miles after including the card's standard 1x earning, which means you're basically buying AA miles for 1.96¢ per mile. American also notes that receiving miles may reduce the tax-deductible portion of your donation, so keep that in mind before participating.